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Custom DNA Synthesis
Custom DNA Price List #1

Unit : Japanese Yen (tax exclusive)
  Synthesis Scale Notes
OLIGO
KIDS
25nmol 0.05µmol 0.2µmol 1µmol
Number of Base *1 11 - 30mer 11 - 30mer 11 - 50mer -99mer -120mer 121-150mer  
Price of Oligo Synthesis
Normal synthesis price 80 120 140 240 300 350 per base
Degenerated base price*2 - - 140 240 300 - per base /more than
0.05µmol scale
Inosine - - 2,000 2,000 3,000 - per base /more than
0.05µmol scale
2'-O-Methylation - - - 2,500 5,000 - Please inquire
Purification *3 (per tube)
Gel Filtration No charge No charge No charge No charge No charge - 11 - 50 mer
Reverse-phase Cartridge Purification 2,000 2,000 2,000 2,000 4,000 - Up to 70 mer
Reverse-phase Cartridge Purification (with TOF/MS data)*4 - 3,500 3,500 3,500 6,000 - Up to 35 mer
HPLC Purification - 6,000 6,000 6,000 12,000 - Up to 120 mer
IEX HPLC Purification - - - 12,000 - - Between 11 and 30 mer (Degenerated base not available)
High Purification (20 -30 mer)*5 - - - - 28,000 - Between 20 and 30 mer (Degenerated base not available)
High Purification (31 -50 mer)*5 - - - - 30,000 - Between 31 and 50 mer (Degenerated base not available)
PAGE Purification - - - 7,000 14,000 14,000 11 - 150 mer
Modification (per tube)
Modified DNA is only available with HPLC purification. 3' end modification is only available for the length between 11 and 50mers.
5' Amination (C6) - - - 7,000 10,000 - Number in brackets means the number of carbon chain linkers.
3' Amination (C6) - - - 8,000 14,000 -
5' Biotin - - - 10,000 20,000 -  
3' Biotin - - - 10,000 20,000 -  
5' Phosphorylation - - - 8,000 12,000 -  
3' Phosphorylation - - - 9,000 16,000 -  
5' FITC(6-FAM) - - - 10,000 20,000 -  
5' TAMRA - - - 15,000 30,000 -  
3' TAMRA - - - 15,000 30,000 -  
5' Rhodamine - - - 15,000 30,000 -  
3' Rhodamine - - - 15,000 30,000 - HPLC Purification Only
5' Thiol *6 (C6) - - - 14,000 24,000 -  
3' Thiol *6 (C3) - - - 15,000 30,000 -  
3' BHQ1 - - - 32,000 - -  
3' BHQ2 - - - 32,000 - -  
5' Texas Red - - - 10,000 - -

Delivered in liquid Reverse-phase Cartridge Purification only

Real Time PCR Probe (15-30mer) - - - 27,000 - - including synthesis and purification fee (lyophilized delivery)
Delivery state (lyophilized) *7
Shipment (No charge for domestic orders, for orders outside Japan, please inquire.)
* Real Time PCR Probe is a probe with modification of 5'FITC(6-FAM) 3'TAMRA.
* Please calculate the total fee as follows: (synthesis fee) X (number of bases) + (purification fee)
   + (modification fee)
* For the shipping fee system, click for detail.


Custom DNA Price List #2
Large Amount Synthesis
* For the orders more than 100mg, "Large Scale Synthesis" is recommended. Click here for the details.
Unit : Japanese Yen (tax exclusive)
Yield Guarantee Synthesis Price HPLC Purification Phosphorothioate Oligo*8 5' FITC 5' Biotin 5' Amination 5' Phosphorylation
per base per tube per tube per tube per tube per tube per tube
1mg 580 20,000 500 27,000 31,000 15,000 28,000
2mg 720 24,000 600 35,000 45,000 21,000 44,000
3mg 860 28,000 700 47,000 61,000 28,000 58,000
4mg 1,000 32,000 800 62,000 81,000 37,000 72,000
5mg 1,140 36,000 900 77,000 101,000 46,000 85,000
Order Acceptance and Shipment
Order Acceptance week FAX E-mail WEB
Mon. through Fri. 15:00 17:00 19:00(*1)
*1 Orders accepted before 19:00 are to be shipped on the next business day
for 11~40 mers oligos with Gel Filtration or Reverse-phase Cartridge
Purification. For the other DNA/RNA synthesis, orders are accepted untill 18:00.
Sat. 15:00 16:30
Sun. & Holidays 12:00
Shipment Mon. through Sat. Shipment is made.
Sun. & Holidays No shipment is made.
Delivery Mon. through Fri. Pl. inquire to HSS head office.
Notice
*1 The fee for 10mer will be charged when the order is under 10mer.
*2 Degenerated base is available for more than 0.05µmol scale.
*3 Each purification grade has applicable number of bases.
Basically, product longer than 71 mer is available with HPLC and PAGE purification only.
Please note that gel filtration for the product shorter than 10 mer is not available.
*4 The molecular weight data of TOF/MS will be enclosed to the product under 35mer.
*5 Combination of HPLC + IEX HPLC purifications are applied for oligos of 20 -30 mers, and HPLC + PAGE purifications for oligos of 31 -50 mers.
*6 Products with Thiol modification have the protecting group on to avoid disulfide linkage. The protocol for deblocking will be enclosed with the shipment of the product.
*7 Products will be lyophilized for delivery with some exceptions. Please inquire for delivery in other state.
*8 Molecular weight will be measured by TOF/MS to ensure Phosphorothioate oligo is correctly produced before shipment.
TOF/MS measurement is available limited to oligo under 35mer.
Phosphorothioate oligo fee is calculated as follows: (the price of Phosphorothioate oligo per position) X (number of positions)
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